Utomhusporträtt av Cecilia Engdahl

Photo: Erik Thor/SUA

About Cecilia's research

Many of us have an elderly relative who has had a fracture, often due to osteoporosis. Fractures lead to reduced mobility, increased risk of other diseases and premature death. Every second woman gets an osteoporosis-related fracture during her lifetime and the risk of fracturs are age-dependent. An activated immune system, for example due to an autoimmune disease or cancer treatment, increases the risk of fractures further and leads to an earlier incidence of fractures. Bone and the immune system are closely linked and the cell that breaks down bone, the osteoclast, is a bone-specific macrophage, and is thereby stimulated by the same proteins that promote immune activation. We try to understand more about the immune system's connection to bone turnover, mainly via osteoclast stimulation, in autoimmune diseases and after bone marrow transplantation (hematopoietic stem cell transplantation). With this knowledge, we want to counteract the increased risk of fractures and to treat it preventively.

Downloadable images

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Photo: Erik Thor/SUA

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In brief

Born: 10th June 1983
Interests: Orienteering, both by myself and as a leader to my own and others' children. There, I can push myself and get really dirty in the pursuit of the next control point, but at the same time feel the peace in the forest.
Other: Riding the e-bike to and from work is me time. Then I can process impressions, so as not to bring too much work home with me and to plan work/the evening or just take a breath.

 

With the Young Academy of Sweden behind me, I hope I can make a difference. Both by spreading curiosity and willingness to do research to younger people, but also by influencing research policy in Sweden.

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